SCHEMBL9398261

SCHEMBL9398261

CCCCc1ncc(/C=C2/C(=O)NC(=O)N2CCCC)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 18/20 1.00
AGTR2 P50052 9/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9398266 1.00 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL9162675 0.92 AGTR1 (0.84) AGTR1AGTR2
SCHEMBL9166606 0.92 AGTR1 (0.84) AGTR1AGTR2
SCHEMBL9162670 0.92 AGTR1 (0.84) AGTR1AGTR2
SCHEMBL9171136 0.87 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL9171125 0.87 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL9162597 0.85 AGTR1 (0.74) AGTR1AGTR2
SCHEMBL9161026 0.85 AGTR1 (0.74) AGTR1AGTR2
SCHEMBL9161036 0.85 AGTR1 (0.74) AGTR1AGTR2
SCHEMBL9167471 0.84 AGTR1 (0.93) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5308853-A Hypotensive agents, antagonists of angiotensin II WARNER-LAMBERT COMPANY (US) 1994-05-03 US disclosed
WO-1993013077-A1 ANGIOTENSIN II RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1993-07-08 WO disclosed