SCHEMBL939883

SCHEMBL939883

COc1[c]c(C(F)(F)F)nc(OC)n1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL939965 0.84
SCHEMBL940350 0.80
SCHEMBL941074 0.78 KDM4E (0.34)
SCHEMBL2267657 0.78 MEN1 (0.33) LMNAMAPT
SCHEMBL940362 0.77 MAPK1 (0.31) MAPK1
SCHEMBL939694 0.76
SCHEMBL938363 0.76 KDM4E (0.37) HSD17B10LMNAMAPT
SCHEMBL939472 0.73 SMN1; SMN2 (0.41) HSD17B10LMNAMAPTMAPK1
SCHEMBL7688147 0.68 CYP1A2 (0.34)
SCHEMBL790812 0.67 HSD17B10 (0.33) HSD17B10LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875606-B2 Herbicides; selectivity between crops and weeds IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2011-01-25 US disclosed
EP-1405853-B1 ISOXAZOLINE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-03 EP disclosed
EP-1405853-A1 ISOXAZOLINE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-04-07 EP disclosed