Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399395 | 0.97 | SPHK1 (0.43) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9399816 | 0.96 | SPHK1 (0.45) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9398885 | 0.96 | SPHK1 (0.45) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9398560 | 0.96 | SPHK1 (0.45) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9433362 | 0.93 | SPHK1 (0.38) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9433861 | 0.91 | OPRL1 (0.38) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9399778 | 0.91 | OPRL1 (0.41) | SPHK1OPRL1SKP2ITGB3ITGA2B | |
| SCHEMBL9398696 | 0.90 | RARB (0.47) | SPHK1OPRL1ITGB3ITGA2BSPHK2 | |
| SCHEMBL9399580 | 0.89 | ITGB3 (0.41) | OPRL1ITGB3ITGA2BSLC6A4 | |
| SCHEMBL9399536 | 0.88 | OPRL1 (0.39) | SPHK1OPRL1SKP2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5179101-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |