SCHEMBL9400375

SCHEMBL9400375

CCCCCCCCCCCCSc1ccc(O)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.46
THRA P10827 1/20 0.46
SERPINE1 P05121 1/20 0.45
APP P05067 4/20 0.42
GPR84 Q9NQS5 5/20 0.41
AR P10275 1/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9142817 1.00 THRB (0.46) THRBTHRASERPINE1APPGPR84
SCHEMBL9244266 1.00 THRB (0.46) THRBTHRASERPINE1APPGPR84
SCHEMBL7442049 0.93 AR (0.46) THRBTHRASERPINE1APPAR
SCHEMBL30726472 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL22075766 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL30726457 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL22075892 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL22075713 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL9140756 0.86 ESR1 (0.49) THRBTHRAAR
SCHEMBL30726469 0.86 ESR1 (0.49) THRBTHRAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed