Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748729 | 0.79 | LTA4H (0.45) | MAPTHPGDTDP1TSHRLTA4H | |
| SCHEMBL2665439 | 0.79 | LTA4H (0.45) | MAPTHPGDTDP1TSHRLTA4H | |
| SCHEMBL1776615 | 0.78 | MAPT (0.48) | MAPTHPGDRAB9ANPC1CRHBP | |
| Hydrochloric Acid SCHEMBL10547103 | 0.77 | MAPT (0.47) | MAPTHPGDRAB9ANPC1CRHBP | |
| SCHEMBL3688619 | 0.77 | LTA4H (0.43) | MAPTHPGDTDP1TSHRLTA4H | |
| SCHEMBL11567886 | 0.76 | CA4 (0.46) | MAPTHPGDRAB9ATDP1TSHR | |
| SCHEMBL2469611 | 0.75 | MAPT (0.47) | MAPTHPGDRAB9ANPC1CRHBP | |
| SCHEMBL37520 | 0.75 | MAPT (0.56) | MAPTHPGDRAB9ANPC1CRHBP | |
| SCHEMBL31531963 | 0.74 | MAPT (0.48) | MAPTHPGDRAB9ANPC1CRHBP | |
| SCHEMBL7899007 | 0.73 | MEN1 (0.55) | MAPTHPGDRAB9ANPC1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310849-A | Amino and ammonium isocyanates, a process for their preparation, their use for the production of polymers containing ammonium groups and the polymers thus produced | WOLFF WALSRODE AG (DE) | 1994-05-10 | — | — | US | disclosed |
| US-4946990-A | CHEMICAL INTERMEDIATE FOR THE PRODUCTION OF POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | disclosed |
| US-4886902-A | HEATING POLYISOCYANATE AND AMINE WITH SILYLATED HYDROXYL GROUP; REACTING ISOCYANATE-ACID HALIDE WITH PRODUCT | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4874857-A | FIBER-REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| US-4870198-A | SILYLATED ALCOHOL OR CARBOXYL GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0320235-A2 | A method for producing aliphatic O-arylurethanes | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0307756-A2 | Process for the preparation of isocyanates and their use in the preparation of polyisocyanates containing ester groups, and some polyisocyanates containing these ester groups | BAYER AG (DE) | 1989-03-22 | — | — | EP | disclosed |
| US-4732711-A | CORRESPONDING SULFONYLISOLYANATE AND THIOISOCYANATE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-22 | — | — | US | disclosed |
| US-3939122-A | Process for the preparation of compounds which contain hydantoin rings | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |