Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401077 | 1.00 | TRPV1 (0.40) | TRPV1KCNH2FAAHMGLLTOP1 | |
| SCHEMBL27448664 | 0.94 | TOP1 (0.39) | TRPV1KCNH2TOP1 | |
| SCHEMBL7984426 | 0.86 | MAOB (0.39) | KCNH2TOP1 | |
| SCHEMBL27477798 | 0.84 | ESR1 (0.47) | TRPV1MGLL | |
| SCHEMBL7542289 | 0.84 | ESR1 (0.47) | TRPV1MGLL | |
| SCHEMBL7783211 | 0.84 | KCNH2 (0.44) | TRPV1KCNH2FAAHMGLL | |
| SCHEMBL19031836 | 0.81 | MAOB (0.60) | KCNH2FAAHTOP1 | |
| SCHEMBL19031835 | 0.81 | MAOB (0.60) | KCNH2FAAHTOP1 | |
| SCHEMBL27544085 | 0.79 | KCNH2 (0.42) | TRPV1KCNH2 | |
| SCHEMBL19031851 | 0.79 | KCNH2 (0.59) | TRPV1KCNH2FAAHTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114602-C | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1242771-A | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2000-01-26 | — | — | CN | disclosed |
| US-5356908-A | Agriculture | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5223523-A | Agriculture | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-29 | — | — | US | disclosed |