Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448664 | 0.88 | TOP1 (0.39) | MAOBTOP1KCNH2 | |
| SCHEMBL9401077 | 0.86 | TRPV1 (0.40) | TOP1KCNH2 | |
| SCHEMBL9401079 | 0.86 | TRPV1 (0.40) | TOP1KCNH2 | |
| SCHEMBL27430275 | 0.83 | KCNH2 (0.37) | KCNH2GPR84 | |
| SCHEMBL9818852 | 0.83 | MAOB (0.42) | MAOBKCNH2 | |
| SCHEMBL4630599 | 0.83 | MAOB (0.42) | MAOBKCNH2 | |
| SCHEMBL27419627 | 0.80 | HIF1A (0.36) | KCNH2 | |
| SCHEMBL1451330 | 0.79 | HIF1A (0.41) | — | |
| SCHEMBL1451333 | 0.79 | HIF1A (0.41) | — | |
| SCHEMBL1071800 | 0.79 | MAOB (0.40) | MAOBTOP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137133-A2 | PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES | BASF SE (DE) | 2023-07-20 | — | — | WO | disclosed |
| CN-100350968-C | Modification of feeding behavior | IMP COLLEGE INNOVATIONS LTD (GB) | 2007-11-28 | — | — | CN | disclosed |
| CN-1596119-A | Modification of feeding behavior | IMP COLLEGE INNOVATIONS LTD (GB) | 2005-03-16 | — | — | CN | disclosed |
| CN-1168711-C | Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use | �ϼ��������Ǵ�ѧ | 2004-09-29 | — | — | CN | disclosed |
| CN-1114602-C | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1350519-A | Reversible aqueous pH Sensitive lipidizing reagents, compositions and methods of use | UNIV SOUTHERN CALIFORNIA (US) | 2002-05-22 | — | — | CN | disclosed |
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| CN-1242771-A | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2000-01-26 | — | — | CN | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0938482-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | Oxis International, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998007714-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | OXIS INTERNATIONAL, INC. (US) | 1998-02-26 | — | — | WO | disclosed |