Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | FGF2 | P09038 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401175 | 0.87 | PDPK1 (0.44) | HCAR2TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL21594820 | 0.83 | FGF2 (0.53) | HCAR2MAOBAKR1B10AKR1B1HPSE | |
| SCHEMBL9401184 | 0.83 | FGF2 (0.53) | HCAR2MAOBAKR1B10AKR1B1HPSE | |
| SCHEMBL8825331 | 0.78 | MAOB (0.51) | MAOB | |
| SCHEMBL29929163 | 0.78 | PDPK1 (0.44) | HCAR2TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL3830803 | 0.74 | PDPK1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL8608514 | 0.74 | GBA1 (0.53) | HCAR2HPSEFGF2TP53CYP3A4 | |
| SCHEMBL8755198 | 0.72 | SLC5A2 (0.50) | MAOB | |
| SCHEMBL9525866 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL7154155 | 0.72 | FGF2 (0.47) | HPSEFGF2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346997-A | Treating hypertension, cystic fibrosis, baldness | MURPHY JAMES G (US) | 1994-09-13 | — | — | US | disclosed |