Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GBA1 | P04062 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818606 | 1.00 | LMNA (0.74) | LMNACYP1A2THPOKMT2AMEN1 | |
| Seprilose SCHEMBL636340 | 1.00 | LMNA (0.74) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL9401393 | 1.00 | LMNA (0.74) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL9401471 | 1.00 | LMNA (0.74) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL9253047 | 1.00 | LMNA (0.74) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL8058955 | 0.99 | LMNA (0.76) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL12429068 | 0.95 | LMNA (0.78) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL10182543 | 0.95 | LMNA (0.78) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL13865179 | 0.95 | LMNA (0.78) | LMNACYP1A2THPOKMT2AMEN1 | |
| SCHEMBL16298765 | 0.95 | LMNA (0.78) | LMNACYP1A2THPOKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004359-A2 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS, INC. (US) | 1992-03-19 | — | — | WO | claimed |
| US-5298494-A | Glucofuranose derivatives | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| WO-1992004359-A2 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS, INC. (US) | 1992-03-19 | — | — | WO | disclosed |