Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 17/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401715 | 0.88 | CACNA1B (0.61) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401771 | 0.86 | CACNA1B (0.48) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401883 | 0.86 | KDM4E (0.55) | CACNA1BHTTKMT2AADORA2B | |
| SCHEMBL9401528 | 0.85 | CACNA1B (0.60) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401615 | 0.85 | CACNA1B (0.61) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL7293440 | 0.85 | CACNA1B (0.64) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401875 | 0.85 | CACNA1B (0.45) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401870 | 0.85 | MAPT (0.49) | CACNA1BADORA3MEN1KMT2ACYP1A2 | |
| SCHEMBL9401541 | 0.85 | CACNA1B (0.55) | CACNA1BADORA3MEN1MLNRNR1I2 | |
| SCHEMBL9401649 | 0.84 | CACNA1B (0.46) | CACNA1BADORA3MEN1MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |