Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 15/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401771 | 0.88 | CACNA1B (0.48) | KDM4ECACNA1BHTTKMT2AHSD17B10 | |
| SCHEMBL9401715 | 0.88 | CACNA1B (0.61) | CACNA1BHTTKMT2A | |
| SCHEMBL9401726 | 0.86 | CACNA1B (0.60) | CACNA1BHTTKMT2AADORA2B | |
| SCHEMBL9401756 | 0.85 | CACNA1B (0.43) | KDM4ECACNA1BALDH1A1GAAMAPT | |
| SCHEMBL9401615 | 0.85 | CACNA1B (0.61) | CACNA1BHTTKMT2A | |
| SCHEMBL7293440 | 0.85 | CACNA1B (0.64) | CACNA1BGAAHTTKMT2A | |
| SCHEMBL9401598 | 0.85 | CACNA1B (0.47) | KDM4ECACNA1BALDH1A1GAAMAPT | |
| SCHEMBL9401579 | 0.84 | CACNA1B (0.46) | KDM4ECACNA1BHTTKMT2AHSD17B10 | |
| SCHEMBL9401766 | 0.84 | CACNA1B (0.46) | KDM4ECACNA1BALDH1A1GAAMAPT | |
| SCHEMBL9401521 | 0.84 | MEN1 (0.52) | CACNA1BALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |