Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 15/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401598 | 0.85 | CACNA1B (0.47) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401485 | 0.85 | CACNA1B (0.43) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401699 | 0.85 | CACNA1B (0.46) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401549 | 0.85 | CACNA1B (0.47) | CACNA1BMEN1KMT2ANR1I2NR3C1 | |
| SCHEMBL9401721 | 0.85 | CYP2C9 (0.57) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401883 | 0.85 | KDM4E (0.55) | CACNA1BKMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9401905 | 0.85 | CACNA1B (0.48) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401766 | 0.85 | CACNA1B (0.46) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9401885 | 0.85 | CACNA1B (0.46) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7299623 | 0.84 | CACNA1B (0.45) | CACNA1BMEN1KMT2ANR1I2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |