Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401912 | 1.00 | GLO1 (0.82) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10666559 | 0.93 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10666578 | 0.93 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10897676 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10848393 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10848396 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10850547 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10901015 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10850544 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10901004 | 0.91 | GLO1 (0.76) | GLO1CYP3A4CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4742069-A | CALCIUM ANTAGONIST, ANTIANGINA, ANTIISCHEMIC, HYPOTENSIVE | HOFFMANN-LA ROCHE INC. (US) | 1988-05-03 | — | — | US | disclosed |