SCHEMBL9401927

SCHEMBL9401927

C[C@@H](NC/C=C/C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.36
MAPT P10636 2/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CTSK P43235 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
NOS1 P29475 2/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401730 1.00 BTN3A1 (0.36) BTN3A1MAPTCA12CA14CTSK
SCHEMBL10445511 1.00 BTN3A1 (0.36) BTN3A1MAPTCA12CA14CTSK
SCHEMBL7376784 0.84 CTSK (0.38) BTN3A1CTSKCA1CA2CA7
SCHEMBL7377349 0.84 CTSK (0.38) BTN3A1CTSKCA1CA2CA7
SCHEMBL10445498 0.84 CTSK (0.38) BTN3A1CTSKCA1CA2CA7
SCHEMBL9401629 0.83 CTSK (0.31) CTSKCA1CA2CA7MEN1
SCHEMBL9401661 0.83 CTSK (0.31) CTSKCA1CA2CA7MEN1
SCHEMBL9401786 0.82 NPSR1 (0.40) MAPTCTSKPOLBALDH1A1NPSR1
SCHEMBL9401474 0.82 NPSR1 (0.40) MAPTCTSKPOLBALDH1A1NPSR1
SCHEMBL7505723 0.80 CA12 (0.36) BTN3A1MAPTCA12CA14CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286869-A Vasodilators and anticoagulants FUJIREBIO KABUSHIKI KAISHA (JP) 1994-02-15 US disclosed
EP-0403957-A2 Optical active 1,4-dihydropyridine derivates FUJIREBIO INC. (JP) 1990-12-27 EP disclosed