Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026501 | 0.85 | AGTR1 (0.54) | AGTAGTR1AGTR2 | |
| SCHEMBL1970464 | 0.85 | AGTR1 (0.56) | AGTAGTR1AGTR2 | |
| SCHEMBL8886621 | 0.84 | AGTR1 (0.56) | AGTAGTR1AGTR2 | |
| SCHEMBL9402028 | 0.83 | AGT (0.58) | AGTAGTR1AGTR2 | |
| SCHEMBL8252592 | 0.83 | AGTR1 (0.55) | AGTAGTR1AGTR2 | |
| SCHEMBL9401999 | 0.83 | AGTR1 (0.54) | AGTAGTR1AGTR2 | |
| SCHEMBL9385090 | 0.83 | AGT (0.61) | AGTAGTR1AGTR2 | |
| SCHEMBL9563478 | 0.83 | AGT (0.52) | AGTAGTR1AGTR2 | |
| SCHEMBL14855371 | 0.82 | AGT (0.60) | AGTAGTR1AGTR2 | |
| SCHEMBL4688038 | 0.82 | AGT (0.60) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0445811-A2 | Nitrogen-containing heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |