Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11113571 | 0.98 | TSHR (0.62) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11021138 | 0.84 | ERCC5 (0.55) | TSHRSMN1; SMN2HPGDL3MBTL1POLB | |
| SCHEMBL10824909 | 0.84 | ALDH1A1 (0.50) | TSHRKMT2AMEN1MAPTHPGD | |
| SCHEMBL11113567 | 0.84 | TSHR (0.55) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL17238643 | 0.83 | TSHR (0.63) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL15422357 | 0.83 | TSHR (0.63) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL10918888 | 0.82 | POLB (0.55) | TSHRKMT2AMAPTALOX15ALDH1A1 | |
| SCHEMBL5313340 | 0.80 | TSHR (0.72) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11220212 | 0.80 | KMT2A (0.70) | TSHRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8898345 | 0.79 | TSHR (0.59) | TSHRKMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138349-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | claimed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | claimed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | claimed |
| EP-0088585-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-01-23 | — | — | EP | claimed |
| US-4472316-A | ANTILIPEMIC AGNETS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | claimed |
| EP-0088585-A1 | 3-Benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-09-14 | — | — | EP | claimed |
| US-5330737-A | Nitrogen-sulfur ligands as opiate receptor drug mimics | MALLINCKRODT MEDICAL, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0138349-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | disclosed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4472316-A | ANTILIPEMIC AGNETS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0032748-B1 | THIOPHENE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4460601-A | Dipeptides having a methionine residue and possessing a protective action for the liver | MAGGIONI FARMACEUTICI, S.P.A. (IT) | 1984-07-17 | — | — | US | disclosed |
| US-4421761-A | FUNGICIDES | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0088585-A1 | 3-Benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0088585-A1 | 3-Benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0032748-A1 | Thiophene derivatives | UBE INDUSTRIES, LTD. (JP) | 1981-07-29 | — | — | EP | disclosed |