Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065786 | 0.85 | TSHR (0.41) | TSHR | |
| SCHEMBL23596518 | 0.83 | TSHR (0.48) | TSHRRGS12BACE1PTGER3TDP1 | |
| SCHEMBL6312105 | 0.83 | TSHR (0.42) | TSHRRGS12BACE1TDP1 | |
| SCHEMBL16597503 | 0.83 | TSHR (0.48) | TSHRRGS12BACE1PTGER3TDP1 | |
| SCHEMBL98976 | 0.83 | TSHR (0.48) | TSHRRGS12BACE1PTGER3TDP1 | |
| SCHEMBL5794301 | 0.81 | TSHR (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL10768543 | 0.81 | TSHR (0.39) | TSHRPTGER3 | |
| SCHEMBL9402143 | 0.79 | TSHR (0.44) | TSHRRGS12BACE1PTGER3TDP1 | |
| SCHEMBL9360332 | 0.79 | TSHR (0.44) | TSHRRGS12BACE1PTGER3TDP1 | |
| SCHEMBL7823880 | 0.79 | TSHR (0.39) | TSHRRGS12BACE1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |