SCHEMBL5794301

SCHEMBL5794301

CC(C(Cl)Br)C1NC(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3065786 0.84 TSHR (0.41) TSHR
SCHEMBL9402162 0.81 TSHR (0.46) TSHRMEN1KMT2A
SCHEMBL7823880 0.79 TSHR (0.39) TSHR
SCHEMBL5592332 0.76 TSHR (0.41) TSHRMEN1KMT2A
SCHEMBL7732791 0.74 TSHR (0.42) TSHR
SCHEMBL23596518 0.74 TSHR (0.48) TSHRMEN1KMT2A
SCHEMBL6312105 0.74 TSHR (0.42) TSHR
SCHEMBL16597503 0.74 TSHR (0.48) TSHRMEN1KMT2A
SCHEMBL98976 0.74 TSHR (0.48) TSHRMEN1KMT2A
SCHEMBL14522150 0.73 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006026048-A2 BLEACHING WITH IMPROVED WHITENING THE CLOROX COMPANY (US) 2006-03-09 WO claimed
US-20060046946-A1 Adding to wash water a granule or tablet containing a hypohalite-generating compound, a bromide-releasing compound, a fluorescent whitener; increases the measured textile whitening performance versus a control by a Delta W value of greater than 3.0 THE CLOROX COMPANY 2006-03-02 US claimed
US-5753602-A COMPRISING HALOGEN RELEASE AGENT, ANIONIC SURFACTANT, FILLERS, DISSOLUTION CONTROLLERS THE BLOCK DRUG COMPANY (US) 1998-05-19 US claimed