Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873410 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9402500 | 0.83 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL9402478 | 0.83 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL9402357 | 0.83 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL7311106 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL13474406 | 0.82 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8393708 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL3630129 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7316455 | 0.82 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9402282 | 0.82 | AGTR1 (0.49) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |