Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.68 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402269 | 0.96 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9402349 | 0.95 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9402253 | 0.95 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9402258 | 0.95 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9402516 | 0.93 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9402212 | 0.93 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9402502 | 0.93 | AGTR1 (0.79) | AGTR1AGTR2 | |
| SCHEMBL9402240 | 0.92 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9402198 | 0.92 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL9402353 | 0.91 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | claimed |
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |