Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402584 | 0.88 | PLA2G4B (0.64) | PLA2G4BCYP2D6PPARGPPARAKCNH2 | |
| SCHEMBL9402581 | 0.86 | PLA2G4B (0.64) | PLA2G4BCYP2D6PPARGPPARAKCNH2 | |
| SCHEMBL7804122 | 0.81 | PLA2G4B (0.60) | PLA2G4BCYP2D6PPARGPPARAKCNH2 | |
| SCHEMBL9402732 | 0.81 | SMPD1 (0.62) | PLA2G4BCYP2D6SMPD1 | |
| SCHEMBL9402627 | 0.81 | SMPD1 (0.62) | PLA2G4BCYP2D6SMPD1 | |
| SCHEMBL9402734 | 0.81 | SMPD1 (0.62) | PLA2G4BCYP2D6SMPD1 | |
| SCHEMBL8347551 | 0.80 | PLA2G4B (0.64) | PLA2G4BCYP2D6PPARGPPARAKCNH2 | |
| SCHEMBL17320239 | 0.79 | CNR1 (0.61) | PLA2G4BCYP2D6PPARGPPARAKCNH2 | |
| SCHEMBL9402559 | 0.79 | PLA2G4B (0.83) | PLA2G4BPPARGPPARASMPD1GGPS1 | |
| SCHEMBL9164631 | 0.79 | PLA2G4B (0.83) | PLA2G4BPPARGPPARASMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |