Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.64 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402605 | 0.88 | PLA2G4B (0.56) | PLA2G4BPPARAPPARGCYP2D6GGPS1 | |
| SCHEMBL9164631 | 0.86 | PLA2G4B (0.83) | PLA2G4BPPARAPPARGPTPN11GGPS1 | |
| SCHEMBL9717034 | 0.86 | PLA2G4B (0.83) | PLA2G4BPPARAPPARGPTPN11GGPS1 | |
| SCHEMBL9402559 | 0.86 | PLA2G4B (0.83) | PLA2G4BPPARAPPARGPTPN11GGPS1 | |
| SCHEMBL31473502 | 0.86 | PLA2G4B (0.83) | PLA2G4BPPARAPPARGPTPN11GGPS1 | |
| SCHEMBL1195580 | 0.84 | PLA2G4B (0.81) | PLA2G4BPPARAPPARGCYP2D6PTPN11 | |
| SCHEMBL5432048 | 0.80 | PLA2G4B (0.78) | PLA2G4BPPARAPPARGCYP2D6PTPN11 | |
| SCHEMBL9402724 | 0.80 | SMPD1 (0.61) | PLA2G4BPPARAPPARGPTPN11PLA2G2A | |
| SCHEMBL9402624 | 0.80 | SMPD1 (0.61) | PLA2G4BPPARAPPARGPTPN11PLA2G2A | |
| SCHEMBL9402604 | 0.80 | SMPD1 (0.61) | PLA2G4BPPARAPPARGPTPN11PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |