Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853952 | 0.97 | NR4A2 (0.69) | NR4A2KMT2ANR1H4LPAR1PLA2G4B | |
| SCHEMBL1168167 | 0.92 | NR4A2 (0.71) | NR4A2KMT2ANR1H4LPAR1PLA2G4B | |
| SCHEMBL30869931 | 0.92 | NR4A2 (0.71) | NR4A2KMT2ANR1H4LPAR1PLA2G4B | |
| SCHEMBL3510712 | 0.91 | NR4A2 (0.62) | NR4A2KMT2ANR1H4LPAR1PLA2G4B | |
| SCHEMBL14383942 | 0.89 | DRD2 (0.67) | NR4A2KMT2ANR1H4LPAR1 | |
| SCHEMBL14383507 | 0.89 | DRD2 (0.62) | NR4A2KMT2ANR1H4LPAR1 | |
| SCHEMBL9803295 | 0.88 | KMT2A (0.80) | NR4A2KMT2ANR1H4PLA2G4BAKR1C3 | |
| SCHEMBL3584817 | 0.88 | MAOB (0.71) | NR4A2KMT2ALPAR1FFAR1 | |
| SCHEMBL9325662 | 0.87 | MEN1 (0.68) | NR4A2KMT2ANR1H4LPAR1PLA2G4B | |
| SCHEMBL9402647 | 0.87 | KMT2A (0.73) | NR4A2KMT2ANR1H4PLA2G4BAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |