Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 8/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402553 | 0.91 | PTPN11 (0.62) | PTPN11PPARGPTGESALOX5PLA2G4B | |
| Hydrochloric Acid SCHEMBL9402741 | 0.89 | PTPN11 (0.61) | PTPN11PPARGPTGESALOX5MEN1 | |
| SCHEMBL9402532 | 0.89 | PTPN11 (0.55) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL9402708 | 0.89 | PTPN11 (0.55) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL9402543 | 0.87 | PTPN11 (0.53) | PTPN11PPARGPTGESALOX5MEN1 | |
| SCHEMBL9402567 | 0.84 | PTPN11 (0.50) | PTPN11PPARGPTGESALOX5MEN1 | |
| SCHEMBL9672799 | 0.82 | FFAR1 (0.53) | LMNASLC6A3HDAC6PLA2G4BFFAR1 | |
| SCHEMBL9402535 | 0.81 | PPARG (0.48) | PTPN11PPARGPTGESALOX5PLA2G4B | |
| SCHEMBL9402836 | 0.81 | MGLL (0.48) | FFAR1 | |
| SCHEMBL25788077 | 0.80 | PTPN11 (0.67) | PTPN11PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |