Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677710 | 1.00 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3676213 | 0.89 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9402973 | 0.89 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL344227 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7643207 | 0.85 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL738525 | 0.82 | TSHR (0.92) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29220319 | 0.82 | TSHR (0.92) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11775454 | 0.82 | TSHR (1.00) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL14995 | 0.82 | TSHR (1.00) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15200 | 0.82 | TSHR (1.00) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332779-A | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0460560-A2 | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1991-12-11 | — | — | EP | disclosed |