Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402973 | 1.00 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3677710 | 0.89 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9402807 | 0.89 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9173067 | 0.83 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL26918976 | 0.83 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9067880 | 0.83 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29220319 | 0.81 | TSHR (0.92) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL738525 | 0.81 | TSHR (0.92) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL230028 | 0.81 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11775454 | 0.81 | TSHR (1.00) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398353-B1 | THERMOPLASTIC RESIN COMPOSITION | KANEKA CORP (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-7282535-B2 | Thermoplastic resin composition | KANEKA CORPORATION (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20040147674-A1 | Thermoplastic resin composition | KANEKA CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1398353-A1 | THERMOPLASTIC RESIN COMPOSITION | Kaneka Corporation (JP) | 2004-03-17 | — | — | EP | disclosed |