Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690882 | 0.82 | MAOB (0.51) | MEN1KMT2AALOX5MAOBMRGPRX4 | |
| SCHEMBL8662697 | 0.80 | CASP6 (0.59) | MEN1KMT2ACASP6LMNANPC1 | |
| SCHEMBL22762667 | 0.79 | KDM4E (0.60) | BRD4MEN1KMT2AMAOBLMNA | |
| SCHEMBL11829865 | 0.79 | BRD4 (0.59) | BRD4MEN1KMT2AMAOBLMNA | |
| SCHEMBL11650244 | 0.78 | BRD4 (0.58) | BRD4MEN1KMT2AMAOBLMNA | |
| SCHEMBL9724661 | 0.78 | MAOB (0.60) | BRD4MEN1KMT2AMAOBLMNA | |
| SCHEMBL2993876 | 0.78 | BRD4 (0.69) | BRD4MEN1KMT2A | |
| SCHEMBL28451935 | 0.78 | BRD4 (0.58) | BRD4MEN1KMT2AMAOBMRGPRX4 | |
| SCHEMBL4895612 | 0.77 | BRD4 (0.57) | BRD4MEN1KMT2AMAOBLMNA | |
| SCHEMBL3997171 | 0.77 | BRD4 (0.60) | BRD4MEN1KMT2AMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |