SCHEMBL940346

SCHEMBL940346

NS(=O)(=O)c1cc(C(=O)Cl)ccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 18/20 0.59
CA2 P00918 18/20 0.59
MMP2 P08253 2/20 0.56
CA7 P43166 3/20 0.55
CA13 Q8N1Q1 3/20 0.55
CA12 O43570 2/20 0.52
CA6 P23280 2/20 0.52
CA9 Q16790 2/20 0.52
CA3 P07451 1/20 0.51
CA4 P22748 1/20 0.51
CA5A P35218 1/20 0.51
CA14 Q9ULX7 1/20 0.51
CA5B Q9Y2D0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31018987 1.00 CA1 (0.59) CA1CA2MMP2CA7CA13
Benzoyl Chloride SCHEMBL1081625 0.92 CA1 (0.59) CA1CA2MMP2CA7CA13
SCHEMBL7994545 0.90 MMP2 (0.66) CA1CA2MMP2CA7CA13
SCHEMBL8004443 0.86 CA1 (0.48) CA1CA2MMP2CA7CA13
SCHEMBL31670541 0.85 CA1 (0.63) CA1CA2MMP2CA7CA13
SCHEMBL329732 0.85 CA1 (0.63) CA1CA2MMP2CA7CA13
Sulclamide SCHEMBL476258 0.85 CA1 (0.59) CA1CA2MMP2CA7CA13
SCHEMBL1807551 0.84 CA1 (0.57) CA1CA2MMP2CA7CA13
Hydrochloric Acid SCHEMBL7951765 0.84 CA1 (0.61) CA1CA2MMP2CA7CA13
SCHEMBL7143525 0.84 CA1 (0.58) CA1CA2MMP2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116119833-B Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-09-08 CN claimed
CN-116119833-A Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-05-16 CN claimed
EP-0462016-B1 Process for the industrial preparation of 4-chloro-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl) benzamide ADIR (FR) 1999-09-29 EP claimed
EP-0462017-B1 PROCESS FOR THE INDUSTRIAL PREPARATION OF 3-SULFAMOYL-4-CHLORO-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULFONIC ACID ADIR ET COMPAGNIE (FR) 1993-07-28 EP claimed
US-5110946-A PREPARATION OF 4-CHLORO-3-SULPHAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)-BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULPHONIC ACID ADIR ET COMPAGNIE (FR) 1992-05-05 US claimed
US-5101040-A PROCESS FOR THE INDUSTRIAL PREPARATION OF 4-CHLORO-3-SULFAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE ADIR ET COMPAGNIE (FR) 1992-03-31 US claimed
JP-4279565-A None JP disclosed
JP-6065198-A None JP disclosed
CN-116903557-B Composite sterilization mixture and preparation method thereof 杭州尚善若水环保科技有限公司 2023-12-15 CN disclosed
CN-116903557-A Composite sterilization mixture and preparation method thereof 杭州尚善若水环保科技有限公司 2023-10-20 CN disclosed
CN-116119833-B Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-09-08 CN disclosed
CN-116119833-A Nutrient for water recovery system and preparation method and application thereof 嘉兴沃特泰科环保科技股份有限公司 2023-05-16 CN disclosed
US-9822092-B2 ArylSulfonamide-based matrix metalloprotease inhibitors NOVARTIS AG (CH) 2017-11-21 US disclosed
EP-0088350-A1 Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1983-09-14 EP disclosed
EP-0054892-A1 Synthesis of indolines SCIENCE UNION ET Cie (FR) 1982-06-30 EP disclosed
US-4258059-A Amino-benzamides USV PHARMACEUTICAL CORPORATION (US) 1981-03-24 US disclosed
US-4156732-A Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-29 US disclosed
EP-0000128-A1 Sulfamoylaryl ketones, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1979-01-10 EP disclosed
US-4125614-A DIURETIC HOECHST AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed
US-4061761-A Thiazolidine derivatives HOECHST AKTIENGESELLSCHAFT (DT) 1977-12-06 US disclosed