SCHEMBL9403532

SCHEMBL9403532

CC(C)N(C(=O)COc1nc2ccccc2o1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
ELANE P08246 2/20 0.41
ATM Q13315 1/20 0.40
PPARG P37231 2/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
XDH P47989 1/20 0.38
PPARA Q07869 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GLO1 Q04760 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9403541 0.88 MEN1 (0.48) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL8711219 0.87 MEN1 (0.41) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL9403517 0.87 MEN1 (0.45) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL10830906 0.84 KMT2A (0.56) MEN1KMT2AALDH1A1SMN1; SMN2ELANE
SCHEMBL9022222 0.84 PPARG (0.41) KMT2AALDH1A1SMN1; SMN2TP53ELANE
SCHEMBL10831439 0.82 KMT2A (0.51) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL8108100 0.81 KMT2A (0.37) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL10830857 0.80 TP53 (0.44) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL9682057 0.80 ELANE (0.42) ELANEPPARGXDHPPARA
SCHEMBL10830793 0.79 SMN1; SMN2 (0.41) SMN1; SMN2TP53ELANEPPARGRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537539-A1 2-(2-Benzoxazolyl-oxy)acetamides and their use as herbicides BAYER AG (DE) 1993-04-21 EP claimed
JP-5213912-A None JP disclosed
CN-1036370-C 2-(2-Benzoxazolyl-oxy)acetamides BAYER AG (DE) 1997-11-12 CN disclosed
US-5328897-A Pre- and post-emergence; tolerence by important crops BAYER AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
US-5328897-A Pre- and post-emergence; tolerence by important crops BAYER AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
JP-H05213912-A NEW 2-(2-BENZOXAZOLYL-OXY)-ACETAMIDE BAYER AG 1993-08-24 JP disclosed
EP-0537539-A1 2-(2-Benzoxazolyl-oxy)acetamides and their use as herbicides BAYER AG (DE) 1993-04-21 EP disclosed
EP-0537539-A1 2-(2-Benzoxazolyl-oxy)acetamides and their use as herbicides BAYER AG (DE) 1993-04-21 EP disclosed
US-4602941-A Herbicidally active novel substituted phenylsulfonylurea derivatives and new intermediates therefor NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-07-29 US disclosed
US-4586951-A PLANT GROWTH REGULATORS FOR RICE FIELDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-05-06 US disclosed
US-4552586-A Certain 2-pyridyloxyacetanilides and their use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-11-12 US disclosed
US-4545944-A Herbicidally active novel substituted phenylsulfonylurea derivatives and intermediates therefor NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-10-08 US disclosed
US-4500342-A Herbicidally active substituted phenylsulfonylurea derivatives and intermediates therefor NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-02-19 US disclosed
US-4474600-A Herbicidally active novel substituted phenylsulfonylurea derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-10-02 US disclosed