Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830793 | 0.89 | SMN1; SMN2 (0.41) | PPARGSMN1; SMN2ELANEPPARANPC1 | |
| SCHEMBL9403532 | 0.84 | MEN1 (0.53) | PPARGSMN1; SMN2ELANEALDH1A1PPARA | |
| SCHEMBL10830906 | 0.82 | KMT2A (0.56) | SMN1; SMN2ELANEALDH1A1NPC1RAB9A | |
| SCHEMBL9682057 | 0.80 | ELANE (0.42) | PPARGELANEPPARA | |
| SCHEMBL11189611 | 0.79 | ELANE (0.38) | PPARGSMN1; SMN2ELANEALDH1A1PPARA | |
| SCHEMBL11090608 | 0.79 | PPARG (0.39) | PPARGSMN1; SMN2ELANEALDH1A1PPARA | |
| SCHEMBL8861871 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ELANEALDH1A1NPC1RAB9A | |
| SCHEMBL8105831 | 0.78 | RAB9A (0.38) | PPARGSMN1; SMN2ELANEALDH1A1NPC1 | |
| SCHEMBL8105834 | 0.78 | RAB9A (0.38) | PPARGSMN1; SMN2ELANEALDH1A1NPC1 | |
| SCHEMBL2539650 | 0.78 | MEN1 (0.50) | SMN1; SMN2ELANEALDH1A1PPARANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709380-A2 | N-methyl-,N-isopropyl-heteroaryloxy acetamides | BAYER AG (DE) | 1996-05-01 | — | — | EP | disclosed |