Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024509 | 0.93 | EGFR (0.40) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL8030576 | 0.89 | IDH1 (0.39) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL9728970 | 0.85 | EGFR (0.40) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL9403599 | 0.83 | PDE2A (0.37) | EGFRMEN1KMT2AIDH1PDE2A | |
| SCHEMBL9364376 | 0.83 | GALR3 (0.44) | EGFRGALR3NR2F2TNFRAB9A | |
| SCHEMBL9729823 | 0.82 | EGFR (0.39) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL8024930 | 0.81 | EGFR (0.48) | EGFRCNR1CNR2GALR3NR2F2 | |
| SCHEMBL9403592 | 0.80 | GALR3 (0.55) | EGFRGALR3NR2F2TNFRAB9A | |
| SCHEMBL8025390 | 0.79 | EGFR (0.42) | EGFRCNR1CNR2GALR3NR2F2 | |
| SCHEMBL8025137 | 0.79 | EGFR (0.37) | EGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |