Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024509 | 0.88 | EGFR (0.40) | EGFRKRASSOS1IDH1GALR3 | |
| SCHEMBL8024762 | 0.86 | ATP1A1 (0.42) | EGFRP2RX3ALDH1A1IDH1AURKA | |
| SCHEMBL11108087 | 0.84 | EGFR (0.47) | EGFRP2RX3ALDH1A1KRASSOS1 | |
| SCHEMBL8024317 | 0.84 | EGFR (0.49) | EGFRGALR3NR2F2CNR1CNR2 | |
| SCHEMBL8025127 | 0.84 | EGFR (0.46) | EGFRP2RX3KRASSOS1RPS6KB1 | |
| SCHEMBL7173840 | 0.83 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL7173843 | 0.83 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL8028223 | 0.83 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL7173846 | 0.83 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL8014462 | 0.82 | CYP2D6 (0.49) | EGFRKRASSOS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |