Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 10/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9023271 | 0.99 | KCNH2 (0.50) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL9023276 | 0.99 | KCNH2 (0.50) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL8775506 | 0.83 | KDM4E (0.64) | TOP2ATOP2BALDH1A1KDM4ELMNA | |
| SCHEMBL9023644 | 0.83 | KCNH2 (0.58) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| SCHEMBL9023635 | 0.83 | KCNH2 (0.58) | KCNH2HRH3POLBCACNA1FMAPK1 | |
| Hydrochloric Acid SCHEMBL9023258 | 0.82 | KDM4E (0.63) | TOP2ATOP2BALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9023266 | 0.82 | KDM4E (0.63) | TOP2ATOP2BALDH1A1KDM4ELMNA | |
| SCHEMBL9079484 | 0.82 | CACNA1F (0.67) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9080555 | 0.82 | POLB (0.57) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9500959 | 0.81 | KCNH2 (0.71) | KCNH2HRH3POLBCACNA1FMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6049060-A | — | — | None | — | — | JP | disclosed |
| JP-H0649060-A | 5-AMINO-7-@(3754/24)5-AZASPIRO(2,4)HEPTAN-5-YL)QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1994-02-22 | — | — | JP | disclosed |
| JP-H00649060-A | — | — | 0001-01-01 | — | — | JP | disclosed |