SCHEMBL940369

SCHEMBL940369

CCOc1[c]c(OCC)ncn1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.38
ALDH1A1 P00352 1/20 0.32
AOC3 Q16853 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ENPP1 P22413 1/20 0.31
MAPT P10636 2/20 0.30
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526316 0.72
SCHEMBL2265942 0.68 HPGD (0.34) NQO1ALDH1A1MAPTKDM4E
SCHEMBL4877423 0.66 HPGD (0.33) NQO1
SCHEMBL4347140 0.65 POLB (0.41) NQO1ALDH1A1TSHRMAPTPOLB
SCHEMBL31469712 0.65 NQO1 (0.39) NQO1ALDH1A1ENPP1MAPTMAPK1
SCHEMBL4919180 0.64
SCHEMBL3823157 0.63 KDM4E (0.41) NQO1ALDH1A1AOC3TSHRTDP1
SCHEMBL12936067 0.63 ALDH1A1 (0.39) NQO1ALDH1A1AOC3TSHRTDP1
SCHEMBL16859311 0.62 MEN1 (0.34) NQO1MAPTPOLBMAPK1CYP1A2
SCHEMBL19280814 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875606-B2 Herbicides; selectivity between crops and weeds IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2011-01-25 US disclosed
EP-1405853-B1 ISOXAZOLINE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-03 EP disclosed