SCHEMBL9403869

SCHEMBL9403869

COC(=O)c1cc(S(=O)(=O)O)c(C(=O)OC)s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.47
MAPT P10636 7/20 0.47
LMNA P02545 4/20 0.47
NPSR1 Q6W5P4 2/20 0.46
PPARG P37231 1/20 0.46
NCOA2 Q15596 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
HPGD P15428 4/20 0.44
ALDH1A1 P00352 3/20 0.44
OPRD1 P41143 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
RAB9A P51151 2/20 0.41
ATM Q13315 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 3/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9403870 0.93 KDM4E (0.41) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL3019240 0.84 KDM4E (0.46) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL8779802 0.78 KDM4E (0.40) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL577650 0.76 MAPT (0.45) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL10679238 0.74 OPRD1 (0.44) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL3239031 0.74 KDM4E (0.54) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL8779756 0.73 HPGD (0.45) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL23718257 0.72 KDM4E (0.47) KDM4EMAPTLMNANPSR1PPARG
SCHEMBL11471141 0.71 EDNRA (0.52) MAPTLMNAPPARGHPGDKMT2A
SCHEMBL8888390 0.70 MAPT (0.46) KDM4EMAPTLMNANPSR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6184136-A None JP disclosed
JP-H06184136-A NEW THIOPHENE DERIVATIVE AND ITS PRODUCTION SUMITOMO SEIKA CHEM CO LTD 1994-07-05 JP disclosed