SCHEMBL940395

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL939803	0.90	TNK2 (0.36)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL941500	0.90	MAP2K1 (0.40)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL938736	0.90	RIPK1 (0.39)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL940250	0.89	RIPK1 (0.38)	RIPK1MAP2K1EGFRERBB2ERBB4
	SCHEMBL941469	0.89	AURKA (0.39)	TNK2RIPK1MAP2K1MAPTBTK
	SCHEMBL938738	0.89	MAP2K1 (0.38)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL939325	0.89	MAP2K1 (0.37)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL940039	0.89	MAP2K1 (0.37)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL939563	0.88	MAP2K1 (0.36)	TNK2RIPK1MAP2K1EGFRERBB2
	SCHEMBL940074	0.86	FGFR1 (0.36)	TNK2RIPK1MAP2K1EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.