Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787111 | 1.00 | AR (0.62) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL11646422 | 0.89 | AR (0.61) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL11646428 | 0.89 | AR (0.61) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL5296168 | 0.89 | AR (0.65) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL8846916 | 0.89 | AR (0.65) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL259433 | 0.89 | AR (0.65) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL259434 | 0.89 | AR (0.65) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL8846925 | 0.89 | AR (0.65) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL18812341 | 0.88 | LMNA (0.66) | ARLMNACYP3A4NFKB1HIF1A | |
| SCHEMBL11644576 | 0.87 | LMNA (0.65) | ARLMNACYP3A4NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610357-A1 | TRANSDERMAL THERAPEUTIC SYSTEMS CONTAINING CRYSTALLIZATION INHIBITORS. | SCHERING AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993008795-A1 | TRANSDERMAL THERAPEUTIC SYSTEMS CONTAINING CRYSTALLIZATION INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-13 | — | — | WO | disclosed |