Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019344 | 0.92 | CXCR4 (0.46) | GBA1MEN1ALDH1A1KMT2ARECQL | |
| Hydrochloric Acid SCHEMBL2594025 | 0.90 | CXCR4 (0.44) | GBA1MEN1ALDH1A1KMT2ARECQL | |
| SCHEMBL11449012 | 0.83 | KMT2A (0.56) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL7285585 | 0.83 | KMT2A (0.56) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL7285594 | 0.83 | KMT2A (0.56) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL11485915 | 0.82 | KMT2A (0.58) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL7706864 | 0.81 | MEN1 (0.35) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL7706868 | 0.81 | MEN1 (0.35) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL7710812 | 0.81 | MEN1 (0.35) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL23798166 | 0.79 | MEN1 (0.37) | MEN1ALDH1A1KMT2ARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266978-B1 | Novel physiologically active substances | EISAI R&D MAN CO LTD (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB (SE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB (SE) | 2008-02-28 | — | — | US | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |
| EP-0366914-B1 | 3'-Hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI CHEMICAL IND (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4983602-A | ANTI-TUBERCULOSIS AGENT | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0366914-A2 | 3'-Hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4213985-A | ANTIULCER AND ATNISECRETORY AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | disclosed |
| US-4213984-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051451-A1 | Autoimmune conditions and NADPH oxidase defects | CYBB, NOX1, NOX5 | GBA1 432/4885MEN1 3279/4885ALDH1A1 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.