Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404145 | 0.79 | GBA1 (0.43) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL7706864 | 0.74 | MEN1 (0.35) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL7706868 | 0.74 | MEN1 (0.35) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL7710812 | 0.74 | MEN1 (0.35) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL24209617 | 0.74 | HSD17B10 (0.36) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL13019344 | 0.73 | CXCR4 (0.46) | MEN1KMT2ACHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL18970190 | 0.73 | CHRM5 (0.40) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| SCHEMBL1234464 | 0.73 | SIGMAR1 (0.38) | MEN1KMT2ACHRM5CHRM3HSD17B10 | |
| Hydrochloric Acid SCHEMBL2594025 | 0.72 | CXCR4 (0.44) | MEN1KMT2ACHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL1082345 | 0.71 | HSD17B10 (0.38) | CHRM5CHRM3HSD17B10SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |