Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | PPOX | P50336 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940437 | 1.00 | TDP1 (0.63) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL940434 | 1.00 | TDP1 (0.63) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10377437 | 0.91 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10729150 | 0.91 | MEN1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10379212 | 0.89 | MEN1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10728482 | 0.89 | MEN1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10728481 | 0.88 | MEN1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10377739 | 0.88 | MEN1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL203524 | 0.88 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL203525 | 0.88 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-28 | — | — | US | disclosed |
| US-8420570-B2 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihydroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulations | BAYER CROPSCIENCE AG (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8158557-B2 | Storage-stable formulations of sulfonamides | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20110009263-A1 | SELECTED SALTS OF 3-(5,6-DIHYDRO-1,4,2-DIOXAZIN-3-YL)-N-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)CARBAMOYL]PYRIDINE-2-SULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | disclosed |
| US-20110009264-A1 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | disclosed |
| US-20100255988-A1 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihydroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulations | BAYER CROPSCIENCE AG (DE) | 2010-10-07 | — | — | US | disclosed |
| EP-1449434-B1 | Liquid pesticide composition | NISSAN CHEMICAL IND LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009264-A1 | HERBICIDAL COMBINATION | DDT, AADAC, CYP1B1 | TDP1 2981/4885MEN1 4350/4885KMT2A 465/4885 |
| US-20110009263-A1 | SELECTED SALTS OF 3-(5,6-DIHYDRO-1,4,2-DIOXAZIN-3-YL)-N-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)CARBAMOYL]PYRIDINE-2-SULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | DDT, DYRK4, SLTM | TDP1 2761/4885MEN1 4589/4885KMT2A 228/4885 |
| US-20100255988-A1 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihydroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulations | STS, CYP4X1, DDT | TDP1 4129/4885MEN1 4717/4885KMT2A 1792/4885 |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | DDT, ING2, DNER | TDP1 1495/4885MEN1 2634/4885KMT2A 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.