SCHEMBL203525

SCHEMBL203525

COCC(=NOCC(=O)O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.66
▸ KMT2A Q03164 3/20 0.66
▸ TDP1 Q9NUW8 2/20 0.66
▸ TTR P02766 1/20 0.66
▸ PPOX P50336 1/20 0.66
▸ FFAR1 O14842 5/20 0.48
▸ LMNA P02545 5/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ PTGDR2 Q9Y5Y4 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ POLB P06746 2/20 0.38
▸ CCR6 P51684 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ GPR55 Q9Y2T6 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ PYGL P06737 1/20 0.37
▸ IDO1 P14902 1/20 0.37
▸ HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2809126 1.00 MEN1 (0.66) MEN1KMT2ATDP1TTRPPOX
SCHEMBL203524 1.00 MEN1 (0.66) MEN1KMT2ATDP1TTRPPOX
SCHEMBL29908511 0.92 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
SCHEMBL29414031 0.92 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
SCHEMBL29392315 0.92 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
SCHEMBL8187095 0.92 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
SCHEMBL8187092 0.92 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
SCHEMBL10379059 0.90 MEN1 (0.59) MEN1KMT2ATDP1TTRPPOX
SCHEMBL4099716 0.89 MEN1 (0.65) MEN1KMT2ATDP1TTRPPOX
SCHEMBL10698300 0.89 TDP1 (0.67) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63066156-A — — None — — JP disclosed
US-20240188560-A1 STABLE EMULSIONS ADAMA AGAN LTD. (IL) 2024-06-13 — — US disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 — — EP disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 — — EP disclosed
EP-3088384-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2018-12-12 — — EP disclosed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 — — US disclosed
EP-3088384-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2016-11-02 — — EP disclosed
EP-2155699-B9 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2016-09-14 — — EP disclosed
EP-2639228-B1 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL INC (US) 2016-07-13 — — EP disclosed
US-9339033-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof MERIAL, INC. (US) 2016-05-17 — — US disclosed
US-5571772-A Mixtures of triazine sulfonylurea herbicides and pyrazoline safeners HOECHST SCHERING AGREVO GMBH (DE) 1996-11-05 — — US disclosed
WO-1996031517-A1 HERBICIDAL HETEROARYL-SUBSTITUTED ANILIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-10 — — WO disclosed
WO-1996013977-A2 HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-17 — — WO disclosed
WO-1995033746-A1 CYCLIC SULFONAMIDE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-14 — — WO disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 — — US disclosed
US-5449812-A Substituted benzenesulfonamide derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-12 — — US disclosed
US-5446013-A 2-alkyl-or-aryl-substituted-2-(pyrimidinyl-or-traizinyl-oxy(or-thio))-acotic acid derivatives, process for preparation, and use as herbicides or plant-growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-29 — — US disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 — — EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 — — WO disclosed
JP-S6366156-A MOLECULAR COMPOUND AND PRODUCTION THEREOF ASAHI CHEM IND CO LTD 1988-03-24 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240188560-A1 STABLE EMULSIONS POLR2H, POLR2E, PHOSPHO1 MEN1 4071/4885KMT2A 3666/4885TDP1 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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