Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669829 | 0.87 | MAPT (0.42) | MAPTATMMEN1KMT2AFDPS | |
| SCHEMBL3261592 | 0.84 | — | — | |
| SCHEMBL12244538 | 0.84 | — | — | |
| SCHEMBL10537680 | 0.82 | MEN1 (0.34) | MAPTATMCA2MEN1KMT2A | |
| SCHEMBL12529886 | 0.79 | — | — | |
| Pyrrolidine SCHEMBL2361768 | 0.76 | GBA1 (0.30) | — | |
| Pyrrolidine SCHEMBL2361731 | 0.76 | GBA1 (0.30) | — | |
| SCHEMBL11500196 | 0.74 | MAPT (0.42) | ALDH1A1MAPTATMMEN1KMT2A | |
| SCHEMBL22711078 | 0.72 | OPRM1 (0.34) | — | |
| Piperidine SCHEMBL4181536 | 0.72 | ATM (0.73) | ALDH1A1MAPTATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304548-A | Tether composition joining two furochromones | THE UPJOHN COMPANY (US) | 1994-04-19 | — | — | US | claimed |
| EP-0429464-A1 | BIVALENT LIGANDS EFFECTIVE FOR BLOCKING ACAT ENZYME. | UPJOHN CO (US) | 1991-06-05 | — | — | EP | claimed |
| WO-1990002129-A1 | BIVALENT LIGANDS EFFECTIVE FOR BLOCKING ACAT ENZYME | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | claimed |
| EP-0429464-B1 | BIVALENT LIGANDS EFFECTIVE FOR BLOCKING ACAT ENZYME | UPJOHN CO (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5304548-A | Tether composition joining two furochromones | THE UPJOHN COMPANY (US) | 1994-04-19 | — | — | US | disclosed |
| US-5180717-A | Atherosclerosis treatment and antilipemic agents | THE UPJOHN COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0429464-A1 | BIVALENT LIGANDS EFFECTIVE FOR BLOCKING ACAT ENZYME. | UPJOHN CO (US) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990002129-A1 | BIVALENT LIGANDS EFFECTIVE FOR BLOCKING ACAT ENZYME | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |