Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404906 | 0.86 | CCR5 (0.49) | KMT2ATAAR1KDM4EATMTSHR | |
| SCHEMBL28044188 | 0.83 | KDM4E (0.62) | KMT2ATAAR1KDM4EATMTSHR | |
| SCHEMBL9404994 | 0.82 | KMT2A (0.53) | KMT2ATAAR1KDM4EATMTSHR | |
| SCHEMBL9404886 | 0.82 | KMT2A (0.56) | KMT2ALMNANPC1HTTCCR5 | |
| Hydrochloric Acid SCHEMBL16049971 | 0.81 | KMT2A (0.52) | KMT2ATAAR1KDM4EATMTSHR | |
| SCHEMBL31321697 | 0.81 | KMT2A (0.71) | KMT2ALMNANPC1HTTCYP1A2 | |
| SCHEMBL9404960 | 0.81 | KMT2A (0.55) | KMT2ALMNANPC1HTTCCR5 | |
| SCHEMBL9404899 | 0.81 | KMT2A (0.55) | KMT2ALMNANPC1HTTCCR5 | |
| SCHEMBL17933786 | 0.81 | KMT2A (0.69) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL31321632 | 0.78 | KMT2A (0.58) | KMT2ATSHRMAPK1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431942-B1 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |