Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 15/20 | 0.75 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404747 | 0.94 | STS (0.78) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL486651 | 0.93 | STS (0.79) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL147038 | 0.90 | STS (0.78) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL31508217 | 0.87 | STS (0.81) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL31508390 | 0.86 | STS (0.80) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL4903623 | 0.86 | STS (1.00) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL4903619 | 0.86 | STS (1.00) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL13478102 | 0.85 | STS (0.84) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL3051244 | 0.85 | STS (0.84) | STSSLC22A2NR1I2ABCB11ESR1 | |
| SCHEMBL27488647 | 0.85 | STS (0.78) | STSSLC22A2NR1I2ABCB11ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269696-B1 | TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS | UNIV RUTGERS (US) | 1994-08-03 | — | — | EP | disclosed |
| EP-0269696-A4 | TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS. | UNIV NEW JERSEY (US) | 1990-02-06 | — | — | EP | disclosed |
| US-4883669-A | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0269696-A1 | TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS. | UNIV NEW JERSEY (US) | 1988-06-08 | — | — | EP | disclosed |
| WO-1987007138-A1 | TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS AND PROCESS FOR ADMINISTRATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1987-12-03 | — | — | WO | disclosed |
| US-3989828-A | Mixed esters of estradiol and zeranol | ARIES ROBERT | 1976-11-02 | — | — | US | disclosed |