SCHEMBL486651

SCHEMBL486651

C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@]2(O)CCCCC(=O)O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 15/20 0.79
SLC22A2 O15244 1/20 0.61
NR1I2 O75469 1/20 0.61
ABCB11 O95342 1/20 0.61
ESR1 P03372 1/20 0.61
NR3C1 P04150 1/20 0.61
SHBG P04278 1/20 0.61
PGR P06401 1/20 0.61
CYP3A4 P08684 1/20 0.61
HTR1A P08908 1/20 0.61
ADORA3 P0DMS8 1/20 0.61
AR P10275 1/20 0.61
ADRB3 P13945 1/20 0.61
CYP2B6 P20813 1/20 0.61
TBXA2R P21731 1/20 0.61
UGT1A1 P22309 1/20 0.61
SLC6A2 P23975 1/20 0.61
PDE4A P27815 1/20 0.61
ADORA2A P29274 1/20 0.61
SLC6A4 P31645 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404747 0.97 STS (0.78) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL9404855 0.93 STS (0.75) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3178837 0.87 STS (0.85) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3178828 0.87 STS (0.85) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3046316 0.87 STS (0.85) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3046319 0.87 STS (0.85) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3051243 0.87 STS (0.84) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL3051244 0.87 STS (0.84) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL13478102 0.87 STS (0.84) STSSLC22A2NR1I2ABCB11ESR1
SCHEMBL147038 0.87 STS (0.78) STSSLC22A2NR1I2ABCB11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000613-A1 INJECTABLE CONTROLLED-RELEASE FORMULATIONS OF PROGESTOGEN DRUGS FORDOZ PHARMA CORP. (US) 2026-01-01 US disclosed
US-12433841-B2 Injectable controlled-release formulations of progestogen drugs FORDOZ PHARMA CORP. (US) 2025-10-07 US disclosed
US-20240390289-A1 Dermal Delivery Device AGILE THERAPEUTICS, INC. (US) 2024-11-28 US disclosed
CN-115605187-B Injectable controlled release formulation carrying progestogen drug 福多兹制药公司 2024-09-17 CN disclosed
US-12070520-B2 Dermal delivery device AGILE THERAPEUTICS, INC. (US) 2024-08-27 US disclosed
US-20230057790-A1 INJECTABLE CONTROLLED-RELEASE FORMULATIONS OF PROGESTOGEN DRUGS FORDOZ PHARMA CORP. (US) 2023-02-23 US disclosed
CN-115605187-A Injectable controlled release formulation loaded with progestagen drug 福多兹制药公司(US) 2023-01-13 CN disclosed
CN-109475138-B Multifunctional structured glycidol/non-glycidol materials 美国AAK公司 2022-12-06 CN disclosed
CN-101843603-B Transdermal delivery of hormones without the need of penetration enhancers SCHERING AG 2012-06-27 CN disclosed
EP-2410859-A1 TRANSDERMAL DELIVERY Agile Therapeutics, Inc. (US) 2012-02-01 EP disclosed
WO-2010111488-A1 TRANSDERMAL DELIVERY AGILE THERAPEUTICS, INC. (US) 2010-09-30 WO disclosed
CN-101843603-A Transdermal delivery of hormones without the need of penetration enhancers SCHERING AG 2010-09-29 CN disclosed
CN-1913878-B Transdermal delivery of hormones without penetration enhancers SCHERING AG 2010-05-26 CN disclosed
US-20080166413-A1 Topical pharmaceutical formulations and methods of treatment PHARMAKODEX LIMITED (GB) 2008-07-10 US disclosed
CN-1913878-A Transdermal delivery of hormones without penetration enhancers SCHERING AG (DE) 2007-02-14 CN disclosed
CN-1287877-C Electrokinetic delivery device BIOPHORETIC THERAPEUTIC SYSTEM (US) 2006-12-06 CN disclosed
CN-1437493-A Electrokinetic delivery device BIOPHORETIC THERAPEUTIC SYSTEM (US) 2003-08-20 CN disclosed
US-6080735-A SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES JENAPHARM GMBH & CO. KG (DE) 2000-06-27 US disclosed
CN-1185741-A Skin permeation enhancer compositions using acyl lactylates ALZA CORP (US) 1998-06-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12070520-B2 Dermal delivery device CUTA, KRT18, CD69 STS 3058/4885SLC22A2 458/4885NR1I2 791/4885
US-20240390289-A1 Dermal Delivery Device CUTA, KRT18, CD69 STS 3058/4885SLC22A2 458/4885NR1I2 791/4885
US-20260000613-A1 INJECTABLE CONTROLLED-RELEASE FORMULATIONS OF PROGESTOGEN DRUGS GNRHR, PGR, CYP19A1 STS 96/4885SLC22A2 2215/4885NR1I2 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.