Fluoride

Fluoride

SCHEMBL9405337

Cc1cccc(NCc2ccccc2)c1C.F.F.F.F.F.F.[SbH3]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.57
MAPT P10636 2/20 0.57
TP53 P04637 1/20 0.57
GAA P10253 1/20 0.57
MAPK1 P28482 1/20 0.57
ADRA2C P18825 1/20 0.53
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.49
BRD4 O60885 1/20 0.48
BRD9 Q9H8M2 1/20 0.48
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
NPBWR1 P48145 1/20 0.44
MCHR1 Q99705 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28344249 0.98 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
SCHEMBL2232108 0.96 HSD17B10 (0.60) HSD17B10MAPTTP53GAAMAPK1
Ammonia Solution, Strong SCHEMBL28850909 0.95 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Iodide SCHEMBL29049215 0.95 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Water SCHEMBL29049225 0.95 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Hydrochloric Acid SCHEMBL4373569 0.95 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Bromide SCHEMBL29049211 0.95 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Bicarbonate SCHEMBL29049243 0.90 HSD17B10 (0.58) HSD17B10MAPTTP53GAAMAPK1
Acetic Acid SCHEMBL29049224 0.88 HSD17B10 (0.56) HSD17B10MAPTTP53GAAMAPK1
Oxalic Acid SCHEMBL29049203 0.88 HSD17B10 (0.56) HSD17B10MAPTTP53GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6207126-A None JP disclosed
CN-114716648-A Sealing agent for organic electroluminescent display element 积水化学工业株式会社 2022-07-08 CN disclosed
CN-108699216-B Curable resin composition and sealing agent for organic electroluminescent display element 积水化学工业株式会社 2022-03-18 CN disclosed
JP-H06207126-A RESIN COMPOSITION FOR THERMOSETTING POWDER COATING DAICEL CHEM IND LTD 1994-07-26 JP disclosed