Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281006 | 0.78 | KCNN4 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL3447538 | 0.72 | MAPK1 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL3447537 | 0.72 | MAPK1 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL10762949 | 0.71 | MAPK1 (0.38) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL246162 | 0.69 | ALDH1A1 (0.46) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL8198683 | 0.69 | MAPK1 (0.44) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL10608311 | 0.67 | MAPK1 (0.42) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL10608306 | 0.67 | MAPK1 (0.42) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL13967872 | 0.67 | ALDH1A1 (0.41) | KCNN4MAPK1ALDH1A1ALOX15KMT2A | |
| SCHEMBL1149712 | 0.65 | KCNN4 (0.59) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160824-B2 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0224158-B1 | Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. | HOECHST AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5169979-A | Cures rapidly at low temperatures; surface coatings | HOECHST AG (DE) | 1992-12-08 | — | — | US | disclosed |
| US-5159024-A | Isocyanate blocked with a dialkyl malonate | HOECHST AG (DE) | 1992-10-27 | — | — | US | disclosed |
| US-5084536-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon | HOECHST AG (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0310011-B1 | CURING AGENT AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-4871822-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J | HOECHST AG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0160824-B1 | REACTION PRODUCT OF OLEFINICALLY UNSATURATED COMPOUNDS WITH ACTIVE HYDROGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND 2-COMPONENT COATING SYSTEMS BASED THEREON | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0310011-A1 | Curing agent and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0160824-A1 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-13 | — | — | EP | disclosed |