⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342261 | 0.67 | — | — | |
| SCHEMBL10752249 | 0.65 | — | — | |
| SCHEMBL8068554 | 0.64 | — | — | |
| SCHEMBL6450406 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL627752 | 0.64 | — | — | |
| SCHEMBL25423183 | 0.61 | — | — | |
| SCHEMBL2100159 | 0.61 | — | — | |
| SCHEMBL19039720 | 0.61 | TSHR (0.31) | — | |
| SCHEMBL30986999 | 0.61 | — | — | |
| SCHEMBL6004329 | 0.61 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793928-B1 | PROCESS FOR PURIFYING A SAMPLE OF H38C2 ANTIBODY | PFIZER (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9163227-B2 | Anti-diabetic compounds | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2015-10-20 | — | — | US | disclosed |
| US-20130164310-A1 | ANTI-DIABETIC COMPOUNDS | COVX TECHNOLOGIES IRELAND LIMITED | 2013-06-27 | — | — | US | disclosed |
| EP-0160824-B2 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0224158-B1 | Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. | HOECHST AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5169979-A | Cures rapidly at low temperatures; surface coatings | HOECHST AG (DE) | 1992-12-08 | — | — | US | disclosed |
| US-5159024-A | Isocyanate blocked with a dialkyl malonate | HOECHST AG (DE) | 1992-10-27 | — | — | US | disclosed |
| US-5084536-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon | HOECHST AG (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0310011-B1 | CURING AGENT AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-4871822-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J | HOECHST AG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0160824-B1 | REACTION PRODUCT OF OLEFINICALLY UNSATURATED COMPOUNDS WITH ACTIVE HYDROGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND 2-COMPONENT COATING SYSTEMS BASED THEREON | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0310011-A1 | Curing agent and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0224158-A2 | Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0160824-A1 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-13 | — | — | EP | disclosed |