Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380362 | 0.89 | IDO1 (0.56) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL6476003 | 0.86 | IDO1 (0.54) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL9879256 | 0.84 | IDO1 (0.52) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL9405361 | 0.77 | IDO1 (0.54) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL12402051 | 0.76 | IDO1 (0.44) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL7532634 | 0.76 | IDO1 (0.58) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL2976159 | 0.76 | IDO1 (0.52) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL8386777 | 0.76 | IDO1 (0.52) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL10729674 | 0.75 | IDO1 (0.47) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL30878 | 0.74 | CA12 (0.61) | IDO1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160824-B2 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0224158-B1 | Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. | HOECHST AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5159024-A | Isocyanate blocked with a dialkyl malonate | HOECHST AG (DE) | 1992-10-27 | — | — | US | disclosed |
| US-5084536-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon | HOECHST AG (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0310011-B1 | CURING AGENT AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-4871822-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J | HOECHST AG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0160824-B1 | REACTION PRODUCT OF OLEFINICALLY UNSATURATED COMPOUNDS WITH ACTIVE HYDROGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND 2-COMPONENT COATING SYSTEMS BASED THEREON | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0310011-A1 | Curing agent and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0224158-A2 | Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0160824-A1 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-13 | — | — | EP | disclosed |