Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386777 | 0.86 | IDO1 (0.52) | IDO1ALDH1A1PKMCA12CA1 | |
| SCHEMBL380362 | 0.81 | IDO1 (0.56) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9405361 | 0.79 | IDO1 (0.54) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL6476003 | 0.79 | IDO1 (0.54) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9879256 | 0.77 | IDO1 (0.52) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7532634 | 0.77 | IDO1 (0.58) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9405362 | 0.76 | IDO1 (0.50) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL5452410 | 0.74 | IDO1 (0.55) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL8389197 | 0.74 | IDO1 (0.55) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL14604190 | 0.74 | LTA4H (0.55) | IDO1AGXTLTA4HTAAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781425-B2 | Guanidine compound and asymmetric reaction using the same | TAKASAGO INTERNATIONAL COPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | GEMIN5, PRMT5, SMS | IDO1 731/4885ALDH1A1 2039/4885PKM 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.